PHOREVER is a research and innovation action that aims to develop a disruptive multi-sensing platform with a great medical impact. The platform will enable for the first time the reliable detection of EVs with size down to 140 nm, the detection of EVs with specific biomarkers (proteins) on their surface, and the calculation of the corresponding EV concentrations in the blood while data analysis empowered by artificial intelligence will correlate the measurement data to disease specific medical information.