PHOREVER Publication: Integration of 3D printed microlenses with vertically stacked photonic integrated circuits for biomedical applications

We are excited to announce a new publication from the PHOREVER Project titled “Integration of 3D printed microlenses with vertically stacked photonic integrated circuits for biomedical applications”, published in the SPIE Digital Library (Conference 13900). 🔗 DOI: http://dx.doi.org/10.1117/12.3078100

The paper is authored by K. Obara, C. Zhong, G. Osnabruggea, M. D. Sousa, T. Berns, N. Nijenhuis, M. Milosevic, A. S. Everhardt, F. Schreuder, A. M. Grammatikaki,d, M. Massaouti, H. Avramopoulos.

The study focuses on the detection of extracellular vesicles (EVs) in blood samples, tiny particles that can provide valuable insights for diagnosing diseases such as cancer and cardiovascular conditions. Within this work, researchers developed a compact photonic device that combines three sensing techniques: flow cytometry (FCM), fluorescence sensing, and optical coherence tomography (OCT).

The system is based on silicon nitride photonic integrated circuits enhanced with 3D printed microlenses, enabling the detection of EVs as small as 150 nm. By integrating multiple sensing methods into a single platform, this approach supports the development of compact and efficient point-of-care diagnostic devices, bringing us closer to faster and more precise medical diagnostics.

Explore the full paper here and stay tuned for more updates from the PHOREVER Project!

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