The PHOREVER Project participated in SPIE Photonics West with a poster presentation entitled “Development of 3D-printed micro-lenses at the edge of waveguides of flow cytometry and optical coherence tomography photonic integrated circuits” by Adamantia Maria Grammatikaki (Paper No. 13369-79). The presentation took place on January 29, 2025.
Flow Cytometry (FCM) played a crucial role in healthcare by enabling precise analysis of cell populations, which aided in the diagnosis and treatment of conditions such as cancer and stroke. A cutting-edge biophotonic platform was developed, integrating FCM and Optical Coherence Tomography (OCT) photonic integrated circuits (PICs) to detect Extracellular Vesicles (EVs) as small as 140 nm. The OCT module validated FCM measurements, while innovative micro-optic elements ensured seamless interaction between photonic and fluidic components. With focusing lenses designed for efficient light manipulation across multiple wavelengths, the platform achieved optical losses as low as 0.3 dB, reflecting a remarkable coupling efficiency of 93%. This breakthrough underscored the potential of photonic technologies in advancing healthcare diagnostics.
The paper was co-authored by Adamantia Maria Grammatikaki, Lefteris Gounaridis, Dimitris Gounaridis, Karol Obara, Arnoud Everhardt, Adam Raptakis, Ton van Leeuwen, Edwin van der Pol, Hercules Avramopoulos and Christos Kouloumentas.
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